The dorsolateral prefrontal cortex (DLPFC) is situated in the frontal lobes of the brain, specifically on the lateral or outer surface.


It plays a crucial role in higher cognitive functions, including working memory, cognitive flexibility, and problem-solving.

Executive Functions

DLPFC is often associated with executive functions, such as planning, decision-making, and goal-directed behavior.

Connection to Motor Skills

This region is involved in the planning and execution of voluntary movements, making it essential for coordinated motor skills.

Working Memory Hub

DLPFC is a central hub for working memory, allowing the temporary storage and manipulation of information necessary for ongoing cognitive tasks.

Dysfunction and Disorders

Disruptions in the DLPFC have been linked to various neuropsychiatric disorders, including schizophrenia, ADHD, and mood disorders.

Integration with Sensory Information

It integrates sensory information, helping individuals to adapt and respond to the environment appropriately.

Maturation During Adolescence

The DLPFC undergoes significant maturation during adolescence, contributing to the development of higher-order cognitive abilities.

Inhibitory Control

It is involved in inhibitory control, enabling individuals to suppress inappropriate responses and focus on relevant stimuli.

Neuroimaging Studies

Advances in neuroimaging techniques, such as fMRI, have allowed researchers to better understand the role of DLPFC in cognitive processes, providing insights into normal and pathological brain function.